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What Kratom Is, and How It Works

Kratom University, Level 1, Lesson 1

Estimated read time: 5 minutes

Welcome to Kratom University. The best place to start is the plant itself. Most people who buy kratom know a color and a name from the front of a package, and not much more. By the end of this lesson, you’ll know more than most.

This first lesson covers the tree kratom comes from, what is inside its leaf, and how that leaf becomes the powder you see. It also clears up a few things kratom gets confused with.

It All Starts With a Tree

Kratom is a tree. It is a tall evergreen. It grows in the warm, wet parts of Southeast Asia, in countries like Thailand and Malaysia. Its botanical name is Mitragyna speciosa, and it is a cousin of the coffee plant. The two belong to the same plant family.

Only the leaves are harvested1. The bark, roots, flowers and wood are left alone.

Here’s something many buyers never hear. Every kratom product comes from this one tree. White, green and red are not different plants, and neither are the names printed beside them. It’s all the same leaf, grown in different places and handled in different ways. What the colors and names really mean comes up later in this level.

What’s Inside a Leaf?

Kratom leaves hold natural compounds called alkaloids2. An alkaloid is simply a compound a plant makes on its own. You already know a few. Caffeine is an alkaloid, and so is nicotine.

Kratom has dozens of them. The one you’ll hear about most is mitragynine. University of Florida researchers describe it as the leaf’s main alkaloid. How big a share it holds depends on the tree. When scientists tested wild trees across Thailand, mitragynine made up anywhere from about 28 percent to about 69 percent of the leaf’s alkaloids.

A second one, 7-hydroxymitragynine, shows up in the leaf only in tiny traces. In a 2025 University of Florida study, it averaged just 0.02 to 0.04 percent of the alkaloids drawn from the leaf. It appeared only in certain seasons. As those researchers put it, leaf, fresh or dried, naturally holds only low amounts.

You may have seen products labeled 7-OH. Those are not kratom. They are synthetic, made in a laboratory. On July 6, 2026, the DEA published a proposal to bring those synthetic products under federal drug control. It withdrew that proposal on October 14, 2026 and published a new one in its place. Neither would place mitragynine, the leaf’s main alkaloid, in Schedule I. Both are proposals, and nothing in this lesson is a statement of what the law is3. This course is about natural kratom leaf, so 7-OH products are not part of it. We have never sold 7-OH products and we do not defend them.

Mitragynine and 7-hydroxymitragynine get most of the attention, but they are not the only alkaloids in the leaf.

No Two Leaves Are Quite the Same

Apples from two trees never taste exactly alike. Kratom leaves are the same way. Researchers at Kasetsart University in Thailand tested wild kratom trees across four regions of the country. Some leaves held about three and a half times as much mitragynine as others. Sunlight, humidity, soil and water all played a part.

Those were wild trees in one country, so the numbers do not describe any product you can buy. What they show is that kratom is a crop, and crops vary. Most kratom sold in the United States comes from farmed trees, and the next lesson covers where they grow. Wherever it grows, the leaf varies. That’s why each batch of powder is tested before it is sold.

From Leaf to Powder

The trip from branch to package is short. Leaves are picked by hand. The stems and the thick center vein are pulled out, since they don’t grind well. The leaves are dried, then milled into a fine green powder and sifted so the texture is consistent. Finally, the powder is tested, sealed and shipped out of the country where it grew.

Drying matters more than you might think. It changes what is in the leaf, and it’s part of the story behind kratom’s colors, which you’ll meet later in this level.

What Kratom’s Alkaloids Act On

We want to be upfront about this from day one. Your body has receptors, tiny sites on cells where compounds attach, a bit like a key fitting a lock.

Here’s the sentence we print on every page of this site. Kratom’s alkaloids interact with the same receptor systems that opioids act on. Kratom may be habit-forming. Kratom may be harmful to your health. The FDA has not approved kratom for therapeutic uses.

That does not describe what happens to any one person. It is the reason the next level is all about safety. The level after it covers what taking kratom regularly over months can lead to.

What Kratom Is Not

Three other plants often get mentioned alongside kratom, and they’re easy to tell apart.

Kava4 is the root of a shrub in the pepper family, from the islands of the Pacific. It isn’t related to kratom at all.

Kanna5 is a small succulent from South Africa, with its own, completely different alkaloids.

Coffee6 is kratom’s distant cousin. They share a plant family, but coffee is sold as a seed and kratom as a leaf.

Because they’re different plants, a lab number for kava or kanna tells you nothing about kratom.

Key Takeaways

  • Kratom’s alkaloids interact with the same receptor systems that opioids act on. That’s why this course gives so much room to safety.
  • In one study, some wild leaves held about three and a half times as much mitragynine as others. Two products with the same name may not match.
  • Mitragynine is the leaf’s main alkaloid, but it’s one of dozens. A report that names two alkaloids is only a short list.
  • Anything labeled 7-OH is synthetic and is not kratom. Natural leaf holds only a trace of 7-hydroxymitragynine.
  • Every color and every name comes from the same tree. Read them on a package as labels, not as different plants.

Apply It Now

Grab one kratom product package. If you don’t have one yet, pull up the product page of one you’re considering.

Now start your University Notebook, the one record this course asks you to keep. A spiral notebook or a composition notebook works best, something that stays in one piece rather than loose scrap paper, so you can look back through it as the course goes on and long after it ends. On the first page, write down what the front of the package says, word for word. Over the rest of this level, you’ll follow that one package all the way to its lab report.

Up Next: 1.2 Where Kratom Comes From

Next, we follow the leaf from the riverbanks where it grows to the package in your hand, and meet the country that banned it for 78 years.

Read More

  1. What Is Kratom? ↩Where nearly all the leaf sold in the United States is actually grown, how the export rules shape what arrives, and a lot we sent back because it had not been dried the way its label claimed
  2. Kratom Alkaloids ↩The nine alkaloids one trial measured, how light, leaf age, season and drying move the numbers, and what an alkaloid figure on a lab report can and cannot tell you
  3. Is Kratom Legal in the US? ↩Where kratom is legal and where it is banned, the federal record from 2016 on, and how to check the rules where you live
  4. Kratom vs Kava ↩Why kava’s own food standard leaves the leaf out, how each plant is traditionally prepared, and what testing found inside drinks sold as kava
  5. Kanna vs Kratom ↩Kanna’s disputed botanical name, how it was traditionally prepared, and the permit and royalty that govern its trade in South Africa
  6. Kratom and Coffee ↩What actually makes the two plants relatives, why coffee leaves are sold as a food in Europe, and the one compound found in both

Kratom’s alkaloids interact with the same receptor systems that opioids act on. Kratom may be habit-forming. Kratom may be harmful to your health. The FDA has not approved kratom for therapeutic uses.

Kratom is not intended for long-term or daily use.

This content is educational and is not medical or legal advice. Kratom is not intended to diagnose, treat, cure, or prevent any medical condition or disease. Consult a physician before use, especially if you are pregnant or nursing, have a health condition, or take any medication.

Kratom is intended for adults 21 and over. Kratom is not legal in every jurisdiction. You are responsible for knowing the laws in your location before purchasing or consuming.

Portions of this content were produced with the assistance of AI tools and reviewed by our team.